Given these results, and the fact that miR-19b predicts recurrence in LARC patients [29,30] and is significantly upregulated in CRC and colorectal advanced adenomas (CAA) patients after tumor resection [36], it would be also relevant to evaluate the potential clinical usefulness of PPP2R5E as a predictive biomarker of disease progression in LARC. Here, PPP2R5E is linked to colorectal carcinoma.