As previously reported, Geng et al. used ProxTom, Prox1+/GFPCre (Prox1+/−), Foxc2+/−, Gata2+/−, TgVE, Gata2f/f, and Cx37+/− mice as a primary lymphedema model [67]. The gene discussed is PROX1; the disease is lymphedema.