In previous studies, ARHGAP11A was found to promote the development of basal breast cancer, colon cancer, hepatoma, and gastric cancer by accelerating cell transition from the G1 to S phase, inactivating Rac1B or regulating the TPM1-mediated actin filament stability [29,30,31,32]. The gene discussed is TPM1; the disease is malignant colon neoplasm.