Western blotting results revealed that TMZ-resistant U87MG-R cells highly expressed CYBB along with Nrf2, SOD2, and other epithelial–mesenchymal transition (EMT) markers, such as slug, vimentin, N-Cadherin, and CD44, in addition to the upregulation of cancer stemness marker CD133 (Figure 3C). Here, NFE2L2 is linked to cancer.