IL4 and neoplasm: To examine whether PS affects the proliferation and migration of tumor cells by inhibiting macrophage polarization, a conditioned medium (CM) was collected from IL-4-stimulated BMDMs pretreated with the vehicle (IL-4-CM) or PS (IL-4+PS-CM), and CM from common culture BMDMS without IL-4 or PS treatment acted as the control (Ctrl-CM).