By comparing the ROC curves for the seven parameters analyzed (Table 4), we can observe that the best differentiation of patients with moderate disease activity of RA can be obtained using PDUS (100.00% accuracy), followed by VEGF (97.80% accuracy), MMP-13 (71.50% accuracy), and IL-6 (71.10% accuracy). This evidence concerns the gene VEGFA and rheumatoid arthritis.