Six proteins, including transferrin (TF), prosaposin (PSAP), insulin-like growth factor II (IGF2), insulin-like growth factor-binding protein 7 (IGFBP7), lysosome-associated membrane glycoprotein 2 (LAMP2), and EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1), were found to be differentially expressed between the MS and NMOSD groups. This evidence concerns the gene IGF2 and myeloid sarcoma.