More recently, in 2021, Nevis et al. published the study Use of B-Type Natriuretic Peptide (BNP) and N-Terminal proBNP (NT-proBNP) as Diagnostic Tests in Adults With Suspected Heart Failure: A Health Technology Assessment, to evaluate the diagnostic accuracy, clinical impact and cost-effectiveness of BNP/NTproBNP testing in heart failure. The gene discussed is NPPB; the disease is heart failure.