CSF3 and acute respiratory distress syndrome: G-CSF, MCP-1 and MIP1-α are chemokines that are involved in the rapid recruitment of immune cells and the activation of macrophages, which were shown to be increased in patients with ARDS [35]; therefore, we tested the effect of OP plus ASA treatment on G-CSF, MCP-1 and MIP1-α production in response to different SARS-CoV-2 variants stimulation (Figure 7).