S100A6 and type 1 diabetes mellitus: Among those decreased in the T1D NETome were proteins involved in innate immunity, such as protein S100-A6 (S100A6, 0.44-fold), ELANE (0.30-fold), azurocidin (AZU1, 0.33-fold) and protein S100-P (S100P, 0.53-fold), with significantly lower abundance values compared to those of HC subjects (Figure 5A,C).