CASP3 and gastric cancer: Li et al. showed that ZNF139 is negatively correlated with the GC cell apoptotic index (r = −0.686; p < 0.01) and the underlying molecular mechanism was that ZNF139 can attenuate apoptosis in GC tissues by inhibiting Caspase-3 and Bax while promoting Bcl-2 expression [47].