We assessed NPIIAGG and dN/dSPW levels of six major cancer-related pathways which form two strongly connected gene networks: (i) pathways of AKT, mTOR, and EGFR signaling, and (ii) Notch, WNT, and Hedgehog pathways relative to the whole set of 2972 molecular pathways under study. Here, MTOR is linked to cancer.