SQSTM1 and hepatocellular carcinoma: In addition, analysis of the HPA database showed that the rate of positive SQSTM1/p62 protein immunohistochemistry staining in HCC tissues was higher than that in normal liver tissues (Figure 1D), and the survival period of patients with high SQSTM1/p62 expression was significantly shorter than for patients with low SQSTM1/p62 expression (Figure 1E).