Liu et al., found lower expression levels of LDHC, GAPDHS, and PGK2 in the human testes and sperm with poor motility in men with asthenozoospermia, suggesting that alteration in the expression levels of LDHC, GAPDHS, and PGK2 may lead to male fertility impairment by disrupting the sperms’ ability to move [52,53]. Here, PGK2 is linked to Reduced sperm motility.