In 2019, Kim et al. first identified low HDAC3 protein levels in eutopic endometrium of infertile patients with endometriosis and, consecutively, induced endometriosis in primate and mouse models, which resulted in the diminution of HDAC3 expression, as well as in implantation and decidualization deficiencies [35]. Here, HDAC3 is linked to endometriosis.