In jejunum, piglets subjected to IUGR showed a decline (p < 0.05) in the mRNA expressions of ZO1, CLDN1, OCLN, MUC1 and TFF3, as contrasted with piglets in the NBW group, whereas Eq administration markedly elevated (p < 0.05) the mRNA levels of CLDN1, OCLN and TFF3 in IUGR piglets. Here, TFF3 is linked to fetal growth restriction.