At the end of the experiment (t12), the high-fat diet alone obviously increased the levels of ALT (p < 0.01), ALP activities (p < 0.005), TP, and Glob (p < 0.005) and decreased the A/G ratio (p < 0.005); quinoa intervention, especially high quinoa intake, effectively ameliorated the liver injury induced by hepatic steatosis, which exhibited lower ALT activity (p < 0.05), lower levels of TP (p < 0.005) and Glob (p < 0.01), and a higher A/G ratio than those of rats in the HF group (p < 0.05) (Table 2). This evidence concerns the gene B3GALNT1 and fatty liver disease.