DLGAP2 and autism spectrum disorder: In the last years, the potential epigenetic role of the father in the transmission of behavioral troubles such as autism or autism-like phenotypes to the offspring have been investigated in animal models and recently in humans [103,104], revealing as epigenetic target the paternally imprinted gene Discs-Large Associated Protein 2 (DLGAP2). This gene encodes a membrane protein located on postsynaptic neurons involved in neuronal signaling and synapse organization [110], and is known as an autism/autism spectrum disorder (ASD) and schizophrenia candidate gene [110,111].