HOXB13 and Familial prostate cancer: Moreover, frequencies of other germline mutations were detected in the HOXB13 (0.8% in the prostate cancer cases and 0.2% in the control group), ATM (0.5% in the prostate cancer cases and 0.2% in the control group), and BRCA1 (0.2% in the prostate cancer cases and 0.1% in the control group) genes, in this order [21].