ESPL1 and PTTG1 showed significantly higher respective transcript levels in the CML NR (mean ΔCtESPL1 = 4.53 ± 1.86, FCESPL1 = 4.40, ΔCtPTTG1 = 3.41 ± 1.72, FCPTTG1 = 3.64) and R (mean ΔCtESPL1 = 4.94 ± 01.51, FCESPL1 = 3.13, ΔCtPTTG1 = 3.42 ± 0.78, FCPTTG1 = 1.88) group when compared to the control group (mean ΔCtESPL1 = 5.89 ± 0.76, ΔCtPTTG1 = 4.10 ± 0.65). This evidence concerns the gene PTTG1 and chronic myelogenous leukemia, BCR-ABL1 positive.