Since proinvasive exosomes were found to express EMMPRIN and MMP-2 at high levels, and the role of exosome-bound EMMPRIN for the induction of MMPs is well established [42,43], MMP-2 secretion by medulloblastoma cells after exosome stimulation was explored (schematic representation shown in Figure 4B). The gene discussed is BSG; the disease is medulloblastoma.