Despite these findings, the prognostic significance of these markers, when tested using Kaplan-Meier plots using the GEPIA database, did not provide any prognostic significance except for VIM, which showed bad survival prognosis in patients at high expression, and E-cad, N-cad and ITGAV which presented as bad prognostic indicators when expressed in low levels in ccRCC. This evidence concerns the gene CDH2 and nonpapillary renal cell carcinoma.