FGF1, FGF3, FGF12, and FGF20 were significantly upregulated (p = 0.0377; p = 0.0371; p = 0.0487; p = 0.0088) (Figure 1E–G), whereas FGF4, FGF7, FGF8, FGF11, FGF18, and FGF22 were significantly downregulated in CCA tissues when compared to normal (p < 0.0001) (Figure S2a). This evidence concerns the gene FGF22 and cholangiocarcinoma.