KDR and cancer: Finally, in cancer cells, β integrin subunits are known to interact with a variety of growth factor receptors including the hepatocyte growth factor receptor c-Met, vascular endothelial growth factor receptor-2 (VEGFR-2), epidermal growth factor receptor (EGFR) and the ErbB2 receptor [43,44,45,46,47,48,49,50].