In the analysis of single-cell transcriptomic data from 6 patients with colon cancer (GSE188711), the cells were clustered into the following 13 clusters: B cells, CD4+ memory T cells, CD4+ naive T cells, CD8+ T cells, endothelial cells, epithelial cells, fibroblasts, macrophages, mast cells, monocytes, neutrophils, plasma, and regulatory T cells (Tregs) (Figure 5A). Here, CD4 is linked to malignant colon neoplasm.