Even when Mcl-1 might protect from cell death, particularly apoptosis, many other factors might affect cell death induction downstream of Mcl-1 and MOMP, thus playing a more important role than Mcl-1 in the regulation of apoptosis and radiosensitivity in other prostate cancer cell lines or during prostate cancer progression. The gene discussed is MCL1; the disease is Familial prostate cancer.