Chu et al. combined bioinformatic predictions with proteomic studies to conclude that higher expression levels of calsyntenin-1 (CLSTN1), clusterin (CLU) and neutrophil gelatinase-associated lipocalin (NGAL) proteins are solid serologic biomarkers for patients with lung adenocarcinoma [6]. Here, CLSTN1 is linked to lung adenocarcinoma.