Data mining of the set of primary liver tumors from The Cancer Genome Atlas (TCGA) (https://portal.gdc.cancer.gov), which were analyzed by the same DNA methylation microarray as the one used herein for our initial cancer cell line screening, showed the occurrence of NSUN7 CpG hypermethylation in 41.4% (156 of 377) of liver tumors (Fig. 4A). Here, NSUN7 is linked to cancer.