CD8A and central nervous system cancer: In the results of MCPcounter, fibroblasts, CD8 T cells, and myeloid dendritic cells infiltration were positively correlated with RS (Fig. 7G,I,K), and the K–M curves showed that myeloid dendritic cells had a greater prognostic impact on patients in the low-risk group, CD8 T cells and fibroblasts had a significant impact on the prognosis of patients in the high-risk group (P < 0.001), where fibroblasts infiltration could very significantly affect the survival of glioma patients with a potency that exceeded that of RS (Fig. 7H,J,L).