CD8A and central nervous system cancer: Although the correlation between the abundance of some immune cell infiltrates and RS showed an inconsistent intensity with the TCGA dataset, such as macrophage M2 and CD8 T cells (Figs. S8B,F, S9A,D), this difference may be indicative of variations of gene expression patterns in glioma patients from different countries and regions, almost all the above analyses showed a trend consistent with the results of the TCGA dataset analysis.