Together, expression levels of five RAD DEPs were significantly correlated with both AD-related protein expression and histopathologic rankings (Aβ in SMTG and HIPP, ICAM1 in SMTG, AL1L1 in IPL, TICN3 in SMTG, and PA1B3 in IPL; Fig. 3d), while expression of IRGQ in SMTG correlated only with pathologic protein expression. This evidence concerns the gene IRGQ and Alzheimer disease.