The result of this study also revealed decreasing levels of this biomarker along with the stages of periodontitis, and this is in solidity with Tâlvan et al in 2017,39where IL-10 levels decreased from early to generalized, being the lowest in aggressive periodontitis; thus, it is tempting to speculate that the higher expression of IL-10 accounts for the less severe form of the disease when compared with the progressed state of periodontitis. Here, IL10 is linked to periodontitis.