This definition could be translated on findings of this study, meaning, if periodontitis could be diagnosed by a POC device using IL-17 or IL-10 levels in saliva, patients could easily diagnose their periodontitis at home and visit dental clinics at a suitable time; current disease activity and responses to treatment can be easily monitored at a chair-side providing a comfortable dental experience to the patient. This evidence concerns the gene IL10 and periodontitis.