Diagnostic accuracy was determined by using ROC to evaluate the sensitivity and specificity of each biomarker to differentiate periodontal health from periodontitis and between the different stages of periodontitis.Fig. 7shows that AUC for salivary IL-17 and IL-10 was 0.727 and 0.793, respectively, suggesting a potential to discriminate between periodontal health and periodontitis. This evidence concerns the gene IL10 and periodontitis.