Simultaneously, in the process of inflammation clearance and ameliorating, immune cells play a significant role.[18] Researches have found that high platelet-lymphocyte ratio is associated with arteriovenous fistula stenosis and thrombosis in HD patients.[19] In consequence, HALP has a strong biological basis as an indicator integrating the interactions between nutrition, inflammation, platelet function, and immune function. The gene discussed is NAT10; the disease is Venous thrombosis.