The frequency of axillary lymph node metastasis of PDB in different molecular subtypes was significantly different (p < 0.05).Recognizing the HER‐2 as the dominant subtype of PDB and related breast cancer should prove useful as a diagnostic tool and may assist in development of therapeutic protocols and cures for this disease will be achieved. The gene discussed is ERBB2; the disease is metastatic malignant neoplasm in the lymph nodes.