The results showed that SHOX2 expression was positively associated with CDKN2C, COL6A1, COL6A2, DCHS1, MAPK7 and RSRC1 in LGG (Fig. 3C) and positively associated with CDKN2C, COL6A1, DCHS1 and RSRC1 in GBM (Fig. 3D) via TIMER2. The gene discussed is CDKN2C; the disease is glioblastoma.