Anti-dsDNA, anti-Smith, anti-Ro/SSA, anti-La/SSB, anti-U1RNP and anti-histones: all negative (enzyme linked immunosorbent assays (ELISA) - low sensitivity, high specificity)] [6]; aCL (Anticardiolipin antibody) (IgG < 20 U): 1 506 U; anti-β2GPI (Anti-beta2 glycoprotein 1 antibody) (IgM < 20 U): 34 U; anti-β2GPI (IgG < 50 U): > 6 100 U (ELISA) - signing a moderate to high risk of APS [7]. The gene discussed is APOH; the disease is autoimmune polyendocrinopathy.