It was confirmed that high concentration of FFA C8:0 can promote the biological behavior of PCa cells, and the expression levels of KLF7 and downstream factors are significantly increased after stimulated by FFA C8:0, then we want to verify whether FFA C8:0 promotes the development of PCa by up-regulating the expression of KLF7. This evidence concerns the gene KLF7 and posterior cortical atrophy.