The results demonstrated that the protein expression of four genes (YTHDF1, YBX1, TRMT10C and TRMT61A) was higher in HCC tissues than normal tissues in the CPTAC database (Fig. 4A), and immunochemistry demonstrated that the expression of YBX1 and TRMT10C was higher in HCC than normal tissues (Fig. 4B). The gene discussed is TRMT10C; the disease is hepatocellular carcinoma.