ID3 and colorectal cancer: To study the effect of ID3 on the radiosensitivity of colorectal cancer cells, we constructed ID3 knockdown and control cell lines HCT116-NC, HCT116-ID3 KD, HT-29-NC, HT-29-ID3 KD, and ID3 overexpression cell lines and control cell lines HCT116-PC, HCT116-ID3 OE, HT-29-PC, and HT-29-ID3.