SOD1 and esophageal squamous cell carcinoma: In a study by Zhang et al. [93], CAF-derived CXCL1 was suggested to be accountable for the induction of a radioresistant phenotype in esophageal squamous cancer (ESCC), by promoting a reduction in ROS scavenging enzyme superoxide dismutase 1 (SOD-1) in cancer cells.