NQO1 and invasive breast carcinoma: To address whether HNRNPC binding influences poly(A) site selection in NQO1, we analyzed The Cancer Genome Atlas (TCGA)-Breast Invasive Carcinoma (BRCA) dataset to determine if there was a difference in the ratio of the long and short NQO1 isoforms, resulting from proximal or distal poly(A) site selection, in cells with high or low HNRNPC expression.