Lastly, by correlating the proportion of injured state PTCs cells in different models with the pro-inflammatory and pro-fibrotic scores of the models (Supplemental Fig. S7A, B), we concluded that Maladaptive PTCs and classical Havcr1 injured PTCs but not novel Krt20 PTCs affect the pro- inflammatory and pro-fibrotic levels in different AKI models. This evidence concerns the gene HAVCR1 and acute kidney injury.