ARPC1B and acute kidney injury: Furthermore, by co-analysis of single-cell sequencing data of AKI-PTCs with UUO mouse proteome and phosphorylated proteomics data, we identified a cytoskeleton remodeling-associated protein Arpc1b that was significantly upregulated at both transcriptional, translational, and post-translational modification levels (Fig. 4H, I and Supplemental Fig. S12A–D).