To confirm the regulatory roles of these cytokine(s) in the induction of NOS2 and/or COX2 expressions, MDA-MB231 (MB231) breast cancer cells were stimulated with IFNγ in the presence and absence of TNFα, IL1β, IL17, and the TLR4 agonist lipopolysaccharide (LPS). The gene discussed is IFNG; the disease is breast carcinoma.