Out of 8498 positive autoantibody tests, the most prevalent were RF and anti-CCP (rheumatoid arthritis; 2389 positive autoantibody tests [26% of all positive tests]), anti-Ro and anti-La (Sjogren syndrome; 1391 [15%]), and anti-dsDNA and anti-Smith (systemic lupus erythematosus; 1367 [15%]). This evidence concerns the gene SSB and rheumatoid arthritis.