SRCIN1 and breast cancer: In keeping with these findings, Gene Set Enrichment Analysis (GSEA32,33) of the transcriptomic profiles of a cohort of 1095 BC patients from The Cancer Genome Atlas (TCGA)34, stratified by transcript levels of the SRCIN1 gene, revealed that the HALLMARK_INFLAMMATORY_RESPONSE gene set is one of the top-ranking signatures inversely associated with the SRCIN1 transcript levels (Fig. 1c).