TGFB1 and neoplasm: In particular, p140Cap expression correlated with a remarkable decrease in mRNA for the pro-tumoral genes, Csf3 and Tgfb1, concomitant with an increase of the anti-tumor gene, Il15. Csf3, encoding for the cytokine, Granulocyte-Colony Stimulating Factor (G-CSF), emerged as the top transcriptionally downregulated gene in TuBo-p140Cap cells vs. mock cells (Log2FC: −1.075, p-value: 2.272 × 10−46) (Fig. 3a).