CD8A and neoplasm: Indeed, we show that p140Cap expression associates with a TME characterized by enhanced homing of proinflammatory and anti-tumor immune cells, such as CD8+ T-lymphocytes, NK cells and M1-macrophages, at the expense of cells endowed with immunosuppressive, tumor-promoting activities, such as PMN-MDSCs, regulatory T cells (Tregs) and M2-macrophages.