Some circRNAs implicated in oxidative stress and inflammation-related disorders are circ-PRKCA, circ-ZNF83, circ-PLEKHM3, circ-FNDC3B, circ-102115 circSATB2 and circFOXM1 on which natural products modulation have been investigated in cancers and other disorders (Jiabin et al., 2019; Ji-An et al., 2021; Sifan and Fang, 2021; Xiaoqing et al., 2021; Zhang W. et al., 2022). This evidence concerns the gene PRKCA and cancer.