PLSCR1 and acute promyelocytic leukemia: Various agents, such as phorbol esters, phospholipid scramblase 1, hyaluronan ester, dimethyl sulfoxide (DMSO), carotenoids (from crocus sativus), sesquitorpene lactones, and retinoic acid, can induce the differentiation of acute promyelocytic leukemia (APL) into functional and morphological mature granulocytes (5–11).