IL6 and Mental deterioration: More specifically, several studies showed elevated levels of IL-6 and CRP to be associated with global cognitive decline (Weaver et al., 2002; Yaffe et al., 2003; Jordanova et al., 2007) and lower performance in executive functions (Schram et al., 2007; Trollor et al., 2012) and memory (Elwan et al., 2003; Teunissen et al., 2003; Komulainen et al., 2007; Schram et al., 2007).