Although the most recent American Association for the Study of Liver Disease guidelines for diagnosis and management of AIH classifies anti-LC-1 antibodies as associated with type 2 AIH, it does not include it in its diagnostic requisites, stating “type 2 is characterized by the antibodies to anti-LKM-1, usually in the absence of ANA and SMA” (6). The gene discussed is BTG3; the disease is autoimmune hepatitis.