CD4 and Decreased total neutrophil count: Instead, CD4 T-cell count <200 cells/mm3 was not considered in the adjusted early neutropenia risk model, despite being a confounding factor because 100% of the early neutropenia cases had CD4 T-cell count <200 cells/mm3 at hospital admission, which is consistent with a 6-year longitudinal follow-up study of a cohort of patients living with HIV that used prophylactic TMP/SMX where authors found that the only variable associated with neutropenia was a low baseline CD4 T-cell count [9].