Moreover, whereas some studies showed a good correlation between flortaucipir uptake and measurements of hyperphosphorylated 4-repeat (4R) tau immunostained across regional tissues [9,10], others performing semiquantitative regional lesion counts in autopsied 4R tauopathies did not support flortaucipir having affinity to 4R tau [11]. The gene discussed is MAPT; the disease is tauopathy.